|本期目录/Table of Contents|

[1]黄酉元,王丽志,黄晓燕,等.370 例女性继发性不孕症患者支原体感染分析[J].传染病信息,2017,06:365-367.
 HUANG You-yuan,WANG Li-zhi,HUANG Xiao-yan,et al.Analysis of mycoplasma infection in 370 female patients with secondary infertility[J].Infectious Disease Information,2017,06:365-367.
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370 例女性继发性不孕症患者支原体感染分析(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2017年06期
页码:
365-367
栏目:
论著
出版日期:
2017-12-20

文章信息/Info

Title:
Analysis of mycoplasma infection in 370 female patients with secondary infertility
作者:
黄酉元王丽志黄晓燕卓惠燕廖扬孙朝晖李林海
501010,解放军广州总医院检验科(黄酉元、王丽志、黄晓燕、卓惠燕、廖扬、孙朝晖、李林海)前两位作者对本文有同等贡献,均为第一作者
Author(s):
HUANG You-yuan WANG Li-zhi HUANG Xiao-yan ZHUO Hui-yan LIAO Yang SUN Zhao-hui LI Lin-hai*
Department of Laboratory Medicine, Guangzhou General Hospital of PLA, 501010, China Huang You-yuan and Wang Li-zhi are the first authors who contributed equally to the article
关键词:
支原体感染继发性不孕症
Keywords:
mycoplasma infection secondary infertility
分类号:
R711.6;R375
DOI:
10.3969/j.issn.1007-8134.2017.06.013
文献标识码:
A
摘要:
目的 分析继发性不孕症女性支原体感染状况,为临床诊治提供参考。方法 采用回顾性分析方法,选取解放军广州总医院生殖中心门诊就诊的继发性不孕症女性患者370 例作为不孕组,将同期半年内自然受孕女性300 例作为对照组。收集2 组患者妇科检查数据及解脲支原体和人型支原体培养结果,对所有数据进行统计学分析。结果 不孕组患者解脲支原体和人型支原体的阳性率分别为57.8% 和7.6%,高于对照组(20.0% 和1.7%)(P 均< 0.05);不孕组患者单项感染206 例(55.7%),混合感染18 例(4.9%);不孕组支原体阳性患者其输卵管堵塞、子宫内膜病变、盆腔粘连及流产史的发生率显著高于阴性者(P 均< 0.05)。结论 继发性不孕症患者支原体感染率高,且支原体感染者盆腔输卵管病变发生率增高,提示支原体感染可能是继发性不孕症发病的重要因素之一,育龄妇女应加强支原体的筛查和治疗。
Abstract:
Objective To analyze the role of mycoplasma infection in female patients with secondary infertility, and providereference for clinical diagnosis and treatment. Methods By using retrospective analysis, 370 female patients with secondary infertilitywere selected from Reproductive Center of General Hospital of Guangzhou Military Command of PLA, as infertility group, while 300natural pregnant women served as the control group. Gynecological examination data, results of Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) infection were collected and analyzed statistically. Results The incidence of tubal obstruction, pelvicadhesion, endometrial lesions and abortion were significantly higher in the infertility group than those in the control group (P < 0.05).The positive rates of Uu and Mh were 57.8% and 7.6% in the infertility group, which were significantly higher than those in the controlgroup (20.0%, 1.7%)(P < 0.05). There were 206 cases (55.7%) with single infection and 18 cases (4.9%) with mixed infection inthe infertility group. The incidence of fallopian tubal blockage, endometrial lesions, pelvic adhesion and abortion history in infertilepatients with mycoplasma infection were significantly higher than those in uninfected patients (P < 0.05). Conclusions Secondaryinfertility patients have a high prevalence of mycoplasma, and mycoplasma infected patients are associated with an increased incidenceof pelvic fallopian tube lesions, suggesting that mycoplasma infection is a possible key factors leading to secondary infertility. Women ofchildbearing age should strengthen mycoplasma screening and treatment.

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备注/Memo

备注/Memo:
[基金项目] 广州市产学研协同创新重大专项(201604040003)
[通信作者] 李林海,E-mail: mature303@126.com
更新日期/Last Update: 2017-12-20