|本期目录/Table of Contents|

[1]姜晓曼,杜训波,冯 静,等.阿坝州3 例人感染H7N9 禽流感病例溯源调查分析[J].传染病信息,2018,04:331-333341.
 JIANG Xiao-man,DU Xun-bo,FENG Jing,et al.Traceability investigation and analysis of 3 cases human infection with avian influenza A (H7N9) virus in Aba Prefecture[J].Infectious Disease Information,2018,04:331-333341.
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阿坝州3 例人感染H7N9 禽流感病例溯源调查分析(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2018年04期
页码:
331-333341
栏目:
论 著
出版日期:
2018-08-30

文章信息/Info

Title:
Traceability investigation and analysis of 3 cases human infection with avian influenza A (H7N9) virus in Aba Prefecture
作者:
姜晓曼 杜训波冯 静 黄韦唯 韩德琳
610041,成都市疾病预防控制中心传染病防制科 (姜晓曼、杜训波、冯静、韩德琳),微生物检验科(黄韦唯)
Author(s):
JIANG Xiao-man DU Xun-bo FENG Jing HUANG Wei-wei HAN De-lin*
Department for Infectious Diseases Control, Chengdu Center for Disease Control and Prevention, 610041, China
关键词:
H7N9溯源调查禽流感
Keywords:
H7N9 traceability investigation avian influenza
分类号:
R183
DOI:
10.3969/j.issn.1007-8134.2018.04.007
文献标识码:
A
摘要:
目的 探寻2017 年4 月27 日—4 月30 日报告的3 例阿坝州人感染H7N9 禽流感病例的感染来源,为防控人 感染H7N9 禽流感提供科学依据。方法 运用现场流行病学调查方法收集病例的临床和流行病学资料,采用RT-PCR 方法 检测病例及相关环境样本,分析病例流行病学特征及可能感染来源。 结果 3 例病例发病前10 d 之内均有活禽市场接触史; 病例之间无流行病学联系;病例的73 名密切接触者10 d 医学观察期内均未出现异常症状。3 例病例接触的活禽市场、活 禽来源中转站、中转站下游市场环境均检出H7N9 阳性,外环境H7N9 总阳性率达52.17%(12/23)。其中,笼具表面涂 抹样本阳性率达6/12,环境综合涂抹样本阳性率6/9。结论 本次疫情可能是由外地感染禽类进入我市禽类养殖批发中转站, 通过鸡贩将受感染的禽类贩卖至省内的不同活禽交易市场,病例因暴露在活禽市场而感染致病。建议加强活禽交易市场规 范管理,强化疫情源头控制,推行“规模养殖、集中屠宰、冷链运输、冰鲜上市”模式。  
Abstract:
Objective To identify the possible infection source of 3 cases of human infection with avian influenza A (H7N9) virus in Aba prefecture reported from April 27, 2017 to April 30, 2017 and provide scientific evidence for the prevention and control of avian influenza A (H7N9) virus in human. Methods Clinical and epidemiological data of involved cases were collected by using the on-site epidemiological survey method. Case samples and related environmental samples were detected with RT-PCR. Epidemiological characteristics and possible sources of infection were analyzed. Results All of 3 cases had exposure history to live poultry markets within 10 days before onset. There were no epidemiological correlations among cases and no abnormal symptoms were found in 73 close contacts of 3 cases during the 10-day medical observation period. H7N9 positive samples were detected in live poultry markets which the patients exposed to, live poultry transfer station and its downstream markets. The total positive rate of H7N9 was 52.17% (12/23) among external environment. The positive rate of smear sample on surface of individual ventilated cages was 6/12, and the positive rate of environmental samples was 6/9. Conclusions Infected poultry from other places firstly enters local poultry breeding and wholesale transfer station, then is sold by chicken traders from transfer station to different live poultry markets within Sichuan Province, ultimately those cases exposed to live poultry markets are contaminated by H7N9. It is recommended to strengthen the standardized management of live poultry markets, enhance the control of infection sources, and implement the model of "scale farming, centralized slaughtering, cold chain transportation and chilled marketing".     

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备注/Memo

备注/Memo:
[ 作者单位] 610041,成都市疾病预防控制中心传染病防制科 (姜晓曼、杜训波、冯静、韩德琳),微生物检验科(黄韦唯) [ 通信作者] 韩德琳,E-mail: 370483636@qq.com
更新日期/Last Update: 2018-09-08