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[1]黄叶芳,吴 波,徐 静,等.银甲片联合阿奇霉素治疗支原体感染盆腔炎性疾病的疗效及对炎症因子水平、免疫功能的影响[J].传染病信息,2018,04:364-367.
 HUANG Ye-fang*,WU Bo,XU Jing,et al.Effect of Yinjia tablet combined with azithromycin on mycoplasma infection with pelvic inflammatory disease, inflammatory factor level and immune function[J].Infectious Disease Information,2018,04:364-367.
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银甲片联合阿奇霉素治疗支原体感染盆腔炎性疾病的疗效及对炎症因子水平、免疫功能的影响(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2018年04期
页码:
364-367
栏目:
论 著
出版日期:
2018-08-30

文章信息/Info

Title:
Effect of Yinjia tablet combined with azithromycin on mycoplasma infection with pelvic inflammatory disease, inflammatory factor level and immune function
作者:
黄叶芳吴 波徐 静马小芳
610000,成都中医药大学附属医院妇科(黄叶芳), 检验科( 吴波);6 1 0 0 0 0, 成都中医药大学中医妇科学 2 0 1 5 级(徐静、马小芳)
Author(s):
HUANG Ye-fang* WU Bo XU Jing MA Xiao-fang
Department of Gynecology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, 610000, China
关键词:
银甲片支原体盆腔炎性疾病炎症因子
Keywords:
Yinjia tablet mycoplasma pelvic inflammatory disease inflammatory factor
分类号:
R711.33
DOI:
10.3969/j.issn.1007-8134.2018.04.016
文献标识码:
A
摘要:
目的 分析银甲片联合阿奇霉素治疗支原体感染盆腔炎性疾病的疗效及对炎症因子水平、免疫功能的影响。 方法 选取2016 年1 月—2018 年2 月我院收治的支原体感染盆腔炎性疾病患者82 例,根据治疗方法不同分为对照组和观 察组,对照组患者采用常规抗生素治疗,观察组患者采用常规抗生素治疗加银甲片辅助治疗,分析2 组患者治疗后的临床效果。 结果 观察组患者支原体转阴率为68.29%,对照组为46.34%,观察组患者支原体转阴率高于对照组,差异有统计学 意义(P < 0.05)。观察组患者治疗前后炎症因子、超氧化物歧化酶、丙二醛、CD4+ 及CD8+ T 细胞百分比 、CD4+/ CD8+ T 细胞比值差值水平高于对照组,差异有统计学意义(P 均< 0.05)。结论 银甲片联合阿奇霉素治疗支原体感染盆 腔炎性疾病可提高支原体转阴率,减轻炎症和氧化应激反应程度,改善机体免疫功能。  
Abstract:
Objective To analyze the curative effect of Yinjia tablet combined with azithromycin on mycoplasma infection with pelvic inflammatory disease, inflammatory factor level and immune function. Methods From January 2016 to February 2018, 82 patients with mycoplasma infection and pelvic inflammatory disease were selected from our hospital and divided into control group and observation group according to different treatment methods. The patients in control group were treated with antibiotics. The patients in the observation group were treated with conventional antibiotics plus Yinjia tablet. Clinical effects of 2 groups were analyzed after treatment. Results The mycoplasma negative rate was 68.29% in the observation group and 46.34% in the control group. The mycoplasma negative rate in the observation group was significantly higher than that in the control group (P < 0.05). The difference level before and after treatment in the inflammatory factors, superoxide dismutase, malondialdehyde, CD4+ T cells, CD8+ T cell, and CD4+/CD8+ T cell ratio were significantly higher in the observation group than those in the control group (P < 0.05). Conclusions Yinjia tablet combined with azithromycin in the treatment of mycoplasma infection with pelvic inflammatory disease can increase mycoplasma negative rate, alleviate the inflammation and oxidative stress, and improve the immune function of the body.

参考文献/References


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备注/Memo

备注/Memo:
[ 基金项目 ] 成都中医药大学附属医院科技发展基金(2016- D-YY-22) [ 作者单位] 610000,成都中医药大学附属医院妇科(黄叶芳), 检验科( 吴波);6 1 0 0 0 0, 成都中医药大学中医妇科学 2 0 1 5 级(徐静、马小芳) [ 通信作者 ] 黄叶芳,E-mail: 22654233@qq.com
更新日期/Last Update: 2018-09-08