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[1]林 琳,傅亚均.宫颈上皮内瘤变Ⅰ级合并高危型HPV 感染行宫颈环形电切术与聚焦超声治疗的疗效对比[J].传染病信息,2018,04:368-372.
 LIN Lin,FU Ya-jun.Comparison the therapeutic efficacy of loop electrosurgical excision procedure on cervical intraepithelial neoplasia (grade Ⅰ ) combined with high-risk HPV infection with focused ultrasound[J].Infectious Disease Information,2018,04:368-372.
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宫颈上皮内瘤变Ⅰ级合并高危型HPV 感染行宫颈环形电切术与聚焦超声治疗的疗效对比(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2018年04期
页码:
368-372
栏目:
论 著
出版日期:
2018-08-30

文章信息/Info

Title:
Comparison the therapeutic efficacy of loop electrosurgical excision procedure on cervical intraepithelial neoplasia (grade Ⅰ ) combined with high-risk HPV infection with focused ultrasound
作者:
林 琳傅亚均
401121,重庆两江新区第一人民医院妇产科(林琳、傅亚均)
Author(s):
LIN Lin FU Ya-jun
Department of Gynaecology and Obstetrics, the First People's Hospital of Chongqing Liangjiang New Area, 401121, China
关键词:
宫颈上皮内瘤变高危型HPV宫颈环形电切术聚焦超声临床疗效
Keywords:
cervical intraepithelial neoplasia high-risk human papillomavirus cervical loop electrosurgical excision procedure
分类号:
R737.3
DOI:
10.3969/j.issn.1007-8134.2018.04.017
文献标识码:
A
摘要:
目的 探讨宫颈上皮内瘤变(cervical intraepithelial neoplasia, CIN) Ⅰ 级合并高危型HPV 感染行宫颈 环形电切术(loop electrosurgical excision procedure,LEEP)与聚焦超声治疗的疗效对比。方法 分析2015 年2 月— 2017 年10 月在我院治疗的CIN Ⅰ级患者67 例,据患者选取的治疗方案分为LEEP 组和超声组,LEEP 组给予LEEP 治疗, 超声组给予聚集超声治疗,观察2 组疗效,同时检测手术前后炎性因子水平。结果 超声组阴道出血量、出血时间、排液量、 排液时间和宫颈创面愈合时间分别为(7.50±1.30)ml、(5.55±1.83) d、(9.89±1.90) ml、(6.51±1.15) d 和(4.01±1.15) 周,明显少于LEEP 组(P 均< 0.05);超声组和LEEP 组治疗有效率分别为87.50% 和91.43%,差异无统计学意义(P > 0.05);超声组和LEEP 组治疗后HPV 转阴率分别为93.75% 和94.29%,差异无统计学意义(P > 0.05);结论  LEEP 和聚焦超声治疗CIN Ⅰ级合并高危型HPV 感染均有较好的效果,但聚焦超声治疗术后阴道排液、出血情况轻,宫颈创面愈 合快。    
Abstract:
Objective To investigate and compare the therapeutic effect of loop electrosurgical excision procedure on cervical intraepithelial neoplasia (grade Ⅰ) combined with high-risk HPV infection with focused ultrasound. Methods Sixtyseven CIN Ⅰ patients were selected from February 2015 to October 2017 in our hospital and they were divided into LEEP group and ultrasound group. LEEP group was treated with LEEP, and ultrasound group was treated with focused ultrasound. Therapeutic effect was observed. The levels of inflammatory factors before and after surgery were detected. Results The vaginal bleeding volume, bleeding time, drainage volume, drainage time and the time of cervical wound closure in the ultrasound group were (7.50±1.30) ml, (5.55±1.83) d, (9.89±1.90) ml, (6.51±1.15) d and (4.01±1.15) weeks, which were significantly shorter than those in the LEEP group (P < 0.05); The effective rate of treatment in the ultrasound group and the LEEP group were 87.50% and 91.43%, respectively, and the difference was not statistically significant between 2 groups (P > 0.05). The HPV negative rates in the ultrasound group and the LEEP group were 93.75% and 94.29%, respectively, and the difference was not statistically significant in 2 groups (P > 0.05). Conclusions LEEP and focused ultrasound treatment are both effective in treatment of grade Ⅰ CIN combined with high-risk HPV infection. Moreover, focused ultrasound reduces vaginal discharge and bleeding and accelerates cervical wound healing.     

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备注/Memo

备注/Memo:
[ 作者单位] 401121,重庆两江新区第一人民医院妇产科(林琳、傅亚均)
更新日期/Last Update: 2018-09-08