|本期目录/Table of Contents|

[1]武继玲,陈建国,冯秀清,等.学龄前儿童轮状病毒性腹泻 流行病学及预后的影响因素分析[J].传染病信息,2018,05:454-457.
 WU Ji-ling*,CHEN Jian-guo,FENG Xiu-qing,et al.Epidemiology of rotavirus diarrhea in preschool children and influencing factors of prognosis[J].Infectious Disease Information,2018,05:454-457.
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学龄前儿童轮状病毒性腹泻 流行病学及预后的影响因素分析(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2018年05期
页码:
454-457
栏目:
专题论著
出版日期:
2018-10-30

文章信息/Info

Title:
Epidemiology of rotavirus diarrhea in preschool children and influencing factors of prognosis
作者:
武继玲陈建国冯秀清刘倩萍朱 芸
615000,西昌市人民医院儿科(武继玲、陈建国、 冯秀清);615000,西昌市疾控中心(刘倩萍);615000 西昌, 凉山州第二人民医院儿科(朱芸)
Author(s):
WU Ji-ling* CHEN Jian-guo FENG Xiu-qing LIU Qian-ping ZHU Yun
Department of Pediatrics, Xichang People's Hospital, 615000, China
关键词:
轮状病毒腹泻流行病学预后
Keywords:
 rotavirus diarrhea epidemiology prognosis
分类号:
R725.7;R512.5
DOI:
10.3969/j.issn.1007-8134.2018.05.011
文献标识码:
A
摘要:
目的 探讨学龄前儿童轮状病毒(rotavirus, RV)性腹泻流行病学特征及预后危险因素。方法 采用回顾性研究, 选取2017 年1—12 月西昌市人民医院住院和门诊收治的3 ~ 5 岁RV 性腹泻患儿作为研究对象,收集流行病学信息,并进 行影响患儿预后的单因素和多因素分析。结果 80 例RV 性腹泻患儿中,以3 岁患儿为主,发病月份集中在1 月(27.50 %)、 2 月(17.50%)、11 月(16.25%)、12 月(22.50%);感染病毒以A 组RV 为主(88.75%),其中最常见的基因分型为 G3P[8](57.75%),其次为G9P[8](22.54%)。经治疗后,痊愈率为66.25%,未愈率为33.75%,RV 性腹泻患儿 预后与性别、中枢神经损害无关(P 均> 0.05),与年龄、病程、肝损害、心肌损害、继发肠道细菌感染有关(P 均< 0.05); Logistic 回归分析显示,年龄、肝损害、心肌损害是影响RV 性腹泻患儿预后的独立危险因素。结论 学龄前儿童RV 性腹 泻流行病学以A 组RV 为主,呈秋冬季和早春高发;年龄、肝损害、心肌损害与RV 性腹泻患儿预后密切相关。 
Abstract:
 Objective To investigate the epidemiology of rotavirus (RV) diarrhea in preschool children and risk factors for the prognosis. Methods A retrospective study was conducted among children with RV diarrhea, at the age of 3-5 years old, who were inpatients or outpatients of Xichang People's hospital from January to December in 2017. Their epidemiological information was collected, and univariate and multivariate analyses were performed to determine factors influencing the prognosis of children. Results Among the included 80 children with RV diarrhea, the majority aged 3 years old. The onset of RV diarrhea mainly occurred in January (27.50%), February (17.50%), November (16.25%) and December (22.50%). Group A RV was the main virus causing such infection (88.75%). The most common genotype was G3P[8] (57.75%), followed by G9P[8] (22.54%). The healing rate was 66.25% and the nonhealing rate was 33.75% after treatment. The prognosis of children with RV diarrhea was not related to gender or central nervous system damage (P > 0.05), while it was related to age, course of disease, liver damage, myocardial damage and secondary intestinal bacterial infection (P < 0.05). Logistic regression analysis showed that age, liver damage and myocardial damage were independent risk factors for the prognosis of children with RV diarrhea. Conclusions Group A RV is the main virus causing RV diarrhea in preschool children, and the disease mainly occurs in autumn, winter and early spring. Age, liver damage and myocardial damage are closely related to the prognosis of children with RV diarrhea.        

参考文献/References


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备注/Memo

备注/Memo:
[ 基金项目 ] 四川省卫生和计划生育委员会科研课题(1600326)
[ 作者单位 ] 615000,西昌市人民医院儿科(武继玲、陈建国、 冯秀清);615000,西昌市疾控中心(刘倩萍);615000 西昌, 凉山州第二人民医院儿科(朱芸)
[ 通信作者 ] 武继玲,E-mail: wu28406284aay@163.com
更新日期/Last Update: 2018-10-30