|本期目录/Table of Contents|

[1]张 彦,胡国启,司 丽,等.艾滋病合并肺结核与单纯肺结核患者的临床特点对比分析研究[J].传染病信息,2018,06:552-554.
 ZHANG Yan,HU Guo-qi,SI Li,et al.A comparative study on clinical characteristics of AIDS patients with pulmonary tuberculosis and simple pulmonary tuberculosis patients[J].Infectious Disease Information,2018,06:552-554.
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艾滋病合并肺结核与单纯肺结核患者的临床特点对比分析研究(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2018年06期
页码:
552-554
栏目:
论 著
出版日期:
2018-12-30

文章信息/Info

Title:
A comparative study on clinical characteristics of AIDS patients with pulmonary tuberculosis and simple pulmonary tuberculosis patients
作者:
张 彦胡国启司 丽刘 标刘 朋刘 萍张学武
 236500,界首市人民医院感染科(张彦、胡国启、 刘标、刘朋、刘萍、张学武);236500,界首市疾病预防控制中 心结核科(司丽)
Author(s):
ZHANG Yan HU Guo-qi SI Li LIU Biao LIU Peng LIU Ping ZHANG Xue-wu*
Department of Infectious Diseases, Jieshou People's Hospital, 236500, China
关键词:
艾滋病肺结核临床分析
Keywords:
AIDS pulmonary tuberculosis clinical analysis
分类号:
R512.91;R521 
DOI:
10.3969/j.issn.1007-8134.2018.06.014
文献标识码:
A
摘要:
目的 分析AIDS 合并肺结核与单纯肺结核患者的临床特点,为早期识别与诊断AIDS 合并肺结核提供参考依据。 方法 回顾性分析47 例AIDS 合并肺结核(研究组)和50 例单纯肺结核患者(对照组)病例资料,对比分析2 组患者临床症状、 实验室检查及影像学结果。结果 研究组发热、消瘦及腹泻等发生率均高于对照组,咳嗽、咳痰及咯血等发生率均低于对照组, 差异均具有统计学意义(P 均< 0.05);研究组中63.83% 患者CD4+ T 细胞数< 250/mm3,而对照组只占8.00%,2 组差异 有统计学意义。研究组痰培养阳性率、结核菌素试验阳性率分别为42.6% 和36.2%,对照组为70.0% 和66.0%,研究组明显 低于对照组(P 均< 0.05);研究组病变累及多个肺段、粟粒样结节影、纵膈淋巴结肿大及肺外结核比例较对照组高,合并 空洞的发生率较对照组低(P 均< 0.05);2 组患者均给予抗结核治疗,研究组治愈44 例(93.6%),死亡3 例(6.4%), 对照组治愈率达100%。结论 在AIDS 高发地区应警惕AIDS 合并肺结核的发生,常规进行肺结核的诊断性筛查,必要时 可行实验性抗结核治疗,尽早明确相关诊断并及时予以治疗,以免延误患者病情。  
Abstract:
Objective To explore the clinical features of AIDS patients with pulmonary tuberculosis and simple pulmonary tuberculosis patients, and provide reference basis for early recognition and diagnosis of AIDS complicated with pulmonary tuberculosis. Methods A retrospective analysis was performed among 47 AIDS patients with pulmonary tuberculosis as study group and 50 patients with simple pulmonary tuberculosis as control group. The clinical symptoms, laboratory and imaging findings of patients in 2 groups were compared and analyzed. Results The incidence of fever, weight loss and diarrhea in the study group was higher than that in the control group, while the incidence of cough, expectoration and hemoptysis was lower than that in the control group (P < 0.05). There was a statistically significant difference in the number of patients with CD4+ T cells < 250/mm3 between the study group (63.83%) and the control group (8.00%). The positive rates for sputum culture and for purified protein derivatives tuberculin test (PPD) were 42.6% and 36.2% in the study group, which were obviously lower than those in the control group, 70.0% and 66.0% (P < 0.05). In the study group, the ratio of the lesions involved multiple lung segments, miliary nodules, mediastinal lymphadenopathy, and extrapulmonary tuberculosis was higher than that in the control group, while the incidence rate of combined cavities was lower than that in the control group (P < 0.05). After anti-tuberculosis treatment was given to both groups of patients, 44 patients (93.6%) were cured and 3 patients died (6.4%) in the study group, while the curing rate reached 100% in the control group. Conclusions In the high-prevalence areas of AIDS, the occurrence of AIDS complicated with pulmonary tuberculosis should be emphasized. The diagnostic screening of pulmonary tuberculosis should be routinely performed. An experimental antituberculosis treatment is feasible if necessary. The relevant diagnosis should be confirmed as soon as possible and the treatment is given timely to avoid delaying the patient's condition.    

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备注/Memo

备注/Memo:

[ 作者单位] 236500,界首市人民医院感染科(张彦、胡国启、 刘标、刘朋、刘萍、张学武);236500,界首市疾病预防控制中 心结核科(司丽)
[ 通信作者] 张学武,E-mail: jsxyxk@sina.com
更新日期/Last Update: 2018-12-30