|本期目录/Table of Contents|

[1]陈 皋,邬碧波,吴孟征,等.肺泡灌洗液结核杆菌RNA 和DNA 检测在痰菌阴性肺结核诊断中的临床应用[J].传染病信息,2019,04:344-345+351.
 CHEN Gao*,WU Bi-bo,WU Meng-zheng,et al.Clinical application of tuberculosis RNA and DNA detection in alveolar lavage fluid for diagnosis of sputum negative pulmonary tuberculosis[J].Infectious Disease Information,2019,04:344-345+351.
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肺泡灌洗液结核杆菌RNA 和DNA 检测在痰菌阴性肺结核诊断中的临床应用(PDF)

《传染病信息》[ISSN:1007-8134/CN:11-3886/R]

期数:
2019年04期
页码:
344-345+351
栏目:
论著
出版日期:
2019-09-12

文章信息/Info

Title:
Clinical application of tuberculosis RNA and DNA detection in alveolar lavage fluid for diagnosis of sputum negative pulmonary tuberculosis
文章编号:
1007-8134(2019)04-0344-02
作者:
陈 皋邬碧波吴孟征罗万蓉秦春俊刘舒舒刘建英刘 丽
618000,德阳市人民医院感染科(陈皋、邬碧波、吴孟征、罗万蓉、秦春俊、刘舒舒、刘建英、刘丽 )
Author(s):
CHEN Gao* WU Bi-bo WU Meng-zheng LUO Wan-rong QIN Chun-jun LIU Shu-shu LIU Jian-ying LIU Li
CHEN Gao*, WU Bi-bo, WU Meng-zheng, LUO Wan-rong, QIN Chun-jun, LIU Shu-shu, LIU Jian-ying, LIU Li Department of Infectious Diseases, Deyang People’s Hospital, 618000, China
*Corresponding author, E-mail: 494848467@qq.com
关键词:
痰菌阴性肺结核核酸检测灵敏度
Keywords:
 sputum negative pulmonary tuberculosis nucleic acid detection sensitivity
分类号:
 R521 
DOI:
10.3969/j.issn.1007-8134.2019.04.015
文献标识码:
A
摘要:
目的 观察肺泡灌洗液结核杆菌RNA 和DNA 检测在痰菌阴性肺结核患者中的阳性检出情况。方法 选取 2017 年3 月—2019 年3 月在我院接受检查和治疗且最终确诊为痰菌阴性肺结核的患者为研究对象,所有患者均接受肺泡 灌洗液结核杆菌RNA 和DNA 检测。分析2 种检测方法阳性检出率的差异。结果 结核杆菌RNA 阳性检出率为63.33%, DNA 阳性检出率为33.33%,前者高于后者。结论 结核杆菌RNA 检测对痰菌阴性肺结核具较高灵敏度,优于DNA 检测。 
Abstract:
 Objective To observe the positive detection of tuberculosis RNA and DNA in alveolar lavage fluid in sputum negative patients with pulmonary tuberculosis. Methods From March 2017 to March 2019, patients with sputum negative pulmonary tuberculosis who were examined, diagnosed and treated in our hospital were selected as the subjects. All patients were tested for tuberculosis RNA and DNA in alveolar lavage fluid. The difference of positive detection rate between the 2 methods was analyzed. Results The positive detection rate of tuberculosis RNA and DNA was 63.33% and 33.33% respectively. The former was higher than the latter. Conclusions Tuberculosis RNA detection is highly sensitive to sputum negative pulmonary tuberculosis than DNA detection.  

参考文献/References


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备注/Memo

备注/Memo:

[ 通信作者] 陈皋,E-mail: 494848467@qq.com
更新日期/Last Update: 2019-09-15